BDBM65456 19171-19-8::4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione::Actimid::CC-4047::Pomalyst::US11059801, Compound D-4::US20230271966, Compound Pomalidomide::US9694015, 6.2::pomalidomide
SMILES Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
InChI Key InChIKey=UVSMNLNDYGZFPF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 65456
Affinity DataIC50: 1.20E+3nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
Affinity DataIC50: 63.1nMAssay Description:A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:Thermal stabilities of CRBN-DDB1 in the presence or absence of phthalimide, thalidomide, lenalidomide and pomalidomide were done in the presence of S...More data for this Ligand-Target Pair